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Original research

Journal of modern medicine, Vol. 4, No. 15 (2026)

DENTAL STATUS OF A PATIENT WITH CONNECTIVE TISSUE DYS-PLASIA: A CLINICAL CASE

  • Samatov U.A.✉
  • Samatov M.U.
Received: September 20, 2026Accepted: October 5, 2026Published: October 6, 2026

Abstract

Patients with connective tissue dysplasia frequently develop dentofacial anomalies, dental caries, periodontal disease, and other conditions due to collagen matrix in-sufficiency. The pathogenesis of these disorders is primarily linked to genetic mu-tations and impaired synthesis of collagen, a protein essential for the structural in-tegrity of bones, ligaments, gums, and enamel. According to various authors, the prevalence of connective tissue dysplasia and associated dental disorders can reach up to 80%. Standard dental treatments for these conditions often prove inef­fective, necessitating alternative and personalized therapeutic approaches. With appropriate management, the prog­nosis can be favorable, provided a comprehensive approach is adopted that includes consultations with specialists in related fields, such as rheumatologists, cardiologists, and ophthalmologists.

Keywords

  • connective tissue dysplasia, dental caries, genetic mutations.

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DENTAL STATUS OF A PATIENT WITH CONNECTIVE TISSUE DYS-PLASIA: A CLINICAL CASE — nashruz.uz