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Original research

Journal of modern medicine, Vol. 14, No. 3 (2026)

MODERN METHODS OF TREATMENT OF PATIENTS WITH OBSTRUCTIVE JAUNDICE OF TUMOR ORIGIN

  • Egamberdiev D.M.
  • Tuyev Kh.N.
  • Voxidov U.G
  • Rakhimov S.S
  • Soipov B.B.
Received: August 28, 2026Accepted: August 28, 2026Published: September 4, 2026

Abstract

Objective: To evaluate the clinical significance of modern surgical and minimally invasive biliary decompres­sion methods in patients with obstructive jaundice of tumor origin and to optimize treatment strategies.

Materials and Methods: The treatment outcomes of 235 patients treated at the Republican Specialized Sci­entific and Practical Medical Center of Oncology and Radiology between 2021 and 2026 were analyzed. The main group consisted of 150 patients, while the comparison group included 85 patients. Clinical, laboratory, and instru­mental examination findings were assessed, along with the effectiveness of biliary drainage, endoscopic stenting, percutaneous transhepatic biliary drainage (PTBD), endoscopic ultrasound-guided biliary drainage (EUS-BD), radical, and palliative surgical interventions.

Conclusion: In patients with obstructive jaundice of tumor origin, the treatment strategy should be individu­alized according to tumor localization, the level of biliary obstruction, tumor resectability, and the patient's general condition.

Keywords

  • obstructive jaundice, malignant biliary obstruction, biliary decompression, ERCP, SEMS, PTBD, EUS-BD, cholangitis, pancreaticoduodenectomy, palliative treatment.

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