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Journal of modern medicine, Vol. 14, No. 3 (2026)

PSYCHOEMOTIONAL DISORDERS AND NEUROGENIC FACTORS - CONTEMPORARY ANALYSIS OF PATHOGENETIC MECHANISMS

  • Mamadaliyev B.O.
  • Normatova Sh.A.
Received: July 1, 2026Accepted: July 3, 2026Published: July 8, 2026

Abstract

Psychoemotional disorders have reached epidemic-level indicators globally, affecting 13-14% of the world's population. This article examines the mechanisms by which neurogenic factors - the HPA axis, neurotransmitter im­balance (serotonin, noradrenaline, dopamine), amygdala hyperactivation, and epigenetic processes - contribute to the formation of psychoemotional pathologies. Preventive approaches are analyzed based on clinical epidemiological data.

Keywords

  • neurotransmitter, HPA axis, cortisol, amygdala, hippocampus, neuroplasticity, monoaminergic sys¬tem, dysregulation, psychoemotional stress, limbic system, epigenetics, allostasis, neuroinflammation, serotonin, comorbidity.

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