ANALYSIS OF COMPLICATIONS IN PATIENTS WITH ISCHEMIC HEART DISEASE AND ARTERIAL HYPERTENSION
Kholmatov S., Tulaboyeva ., Tolipova Y.
October 22, 2026pp. 352–357DOI4 views1 downloads
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Original research
Journal of modern medicine, Vol. 3, No. 14 (2026)
PSYCHOEMOTIONAL DISORDERS AND NEUROGENIC FACTORS - CONTEMPORARY ANALYSIS OF PATHOGENETIC MECHANISMS
- Mamadaliyev B.O.✉
- Normatova Sh.A.
Received: July 1, 2026Accepted: July 3, 2026Published: July 8, 2026
Abstract
Psychoemotional disorders have reached epidemic-level indicators globally, affecting 13-14% of the world's population. This article examines the mechanisms by which neurogenic factors - the HPA axis, neurotransmitter imbalance (serotonin, noradrenaline, dopamine), amygdala hyperactivation, and epigenetic processes - contribute to the formation of psychoemotional pathologies. Preventive approaches are analyzed based on clinical epidemiological data.
Keywords
- neurotransmitter, HPA axis, cortisol, amygdala, hippocampus, neuroplasticity, monoaminergic sys¬tem, dysregulation, psychoemotional stress, limbic system, epigenetics, allostasis, neuroinflammation, serotonin, comorbidity.
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