DENTAL STATUS OF A PATIENT WITH CONNECTIVE TISSUE DYS-PLASIA: A CLINICAL CASE
Samatov U., Samatov M.
Journal of modern medicine, Vol. 4, No. 15 (2026)
Pre-eclampsia (PE) remains the leading cause of severe placental disorders, placental insufficiency, and hypoxic lesions of the fetal central nervous system. Early detection of hemodynamic decompensation prevents intrapartum fetal death and disabling neurological outcomes. In this regard, the aim of the study is to investigate the characteristics of fetal cerebral blood flow in pregnancies complicated by pre-eclampsia of varying severity to optimize the management and timing of delivery. Based on a comprehensive analysis of the results of ultrasound and Doppler studies of pregnant women whose pregnancies were complicated by pre-eclampsia, it was established that the progression of pre-eclampsia correlates with a decrease in the pulsatility index (PI) of the middle cerebral artery (MCA) and a critical drop in the cerebroplacental ratio (CPR), reflecting the brain-sparing effect under hypoxic conditions. An algorithm has been developed that allows timely differentiation between the compensated stage of adaptation and critical decompensation. Thus, Doppler assessment of the cerebroplacental complex in pregnant women with PE is a highly accurate method for predicting perinatal outcomes and serves as a key criterion for choosing between prolongation of pregnancy and emergency delivery.
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