EVALUATION OF THE EFFECT OF CELAGRIP ON THE COURSE OF BAKER'S YEAST-INDUCED FEVER IN PREPUBERTAL ANIMALS
Хакимов З., Кутлиева Ф., Рахманов А.
July 28, 2026pp. 424–4300 views0 downloads
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Original research
Journal of modern medicine, Vol. 14, No. 3 (2026)
MORPHOLOGICAL CHANGES IN THE MESENTERIC LYMPH NODES OF RAT OFFSPRING UNDER MATERNAL DIABETES MELLITUS
- Махмудова Ш.И.✉
- Азизова Ф.Х.
Published: July 28, 2026
Abstract
The present study investigated the effect of maternal diabetes mellitus on the postnatal development of mesenteric lymph nodes (MLNs) in rats. Diabetes was induced in female rats prior to pregnancy by alloxan administration, and the offspring were examined between postnatal days 3 and 30. The offspring of diabetic mothers exhibited delayed differentiation of the cortical and medullary regions, the formation of lymphoid follicles and the establishment of interactions among immunocompetent cells occurred more slowly than in the control group. These findings indicate a detrimental effect of maternal diabetes on the development of the immune system in the offspring.
Keywords
- Keywords: maternal diabetes mellitus, postnatal ontogenesis, mesenteric lymph nodes, immune system, alloxan-induced diabetes, morphogenesis, immunocompetent cells, rats.
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